Geoffrey Leigh
MSc.,ND.D.N.Sc.

Magnesium Chloride is First Line Therapy in Nervous System and Cardiovascular System Conditions

• Magnesium is very poorly adsorbed through the digestive tract
• Some extreme cases of magnesium deficiency completely resist oral supplementation
• Even when serum levels may show normal levels of magnesium, this is not a guarantee that magnesium is actually available at a cellular level, where it is needed the most
• Even when successful, oral supplementation can take up to six months to correct the imbalance, and even then, there is no guarantee that the magnesium is available where it is needed most (due to severe body dysfunction caused by the deficiency)

Magnesium is absorbed into the body primarily from the Ileum of the Small Intestine. Some Magnesium is also absorbed via the Colon.
The efficiency of Magnesium absorption varies inversely with quantity of Magnesium consumed:

- Persons consuming the RDA of Magnesium absorb approximately 50% of Magnesium consumed.
- Persons who consume large amounts of Magnesium absorb as little as 25% of Magnesium consumed.
- Persons who consume sub-optimal quantities of Magnesium may absorb as much as 75% of Magnesium ingested.
- The absorption of Magnesium decreases rapidly when more than 200 mg is consumed at one time - it is therefore advisable to take Magnesium supplements in divided doses during the day.
The intestinal absorption of Magnesium declines in tandem with the progression of the Aging Process.

There is a circadian rhythm associated with both the urinary excretion of Magnesium and serum levels of Magnesium:

Maximum Magnesium excretion occurs at night, while serum Magnesium levels peak around midday.

So, the above biochemical  point up some disturbing facts about oral forms of magnesium, which can cost around $35.00 or more
for a months supply of a nutrient which may be very poorly absorbed!

Enter Magnesium Chloride Transdermal, meaning through or via the skin. There exist today an infinite number of patents and patents pending
for the transdermal delivery of drugs and nutrients. The best know is of course Nicotine patch's to quit smoking.

Using magnesium chloride transdermally results in the rapid cellular-uptake of magnesium through the skin. By bypassing the digestive system all together, one does not need to focus on the many digestive problems that may hinder the biovailability of magnesium.

Following are just some of the health benefits of magnesium.

Magnesium - Health Benefits []

Introduction

This section outlines the biological function and therapeutic applications of Magnesium.


Health Benefits of Magnesium

Abnormally low circulating Blood levels of Magnesium is known as Hypomagnesemia.

Adrenal System
Magnesium may improve the function of the Adrenal Glands.

Cardiovascular System
[View Magnesium's Cardiovascular System Health Benefits]

Cells
Magnesium may modulate the electrical potential of Cell Membranes and may help to maintain the permeability of Cell Membranes: [more info]

- Magnesium may help to maintain the proper electrical charge gradient across Cell Membranes.

Magnesium may facilitate the survival of Fibroblasts. references
Magnesium may inhibit the age-related shortening of Telomeres. references

Digestive System
Magnesium Sulfate (Epsom Salts) is a good laxative for Constipation (it reduces the normal absorption of Water from the Intestine, thereby causing Bowel Movement). references
Diarrhea may occur as a symptom of Magnesium deficiency and Diarrhea may cause the excessive excretion of Magnesium. references

Magnesium may help to prevent Gallstones. references
Magnesium may alleviate some cases of Heartburn. [more info]
Nausea may occur as a symptom of Magnesium deficiency. references
Magnesium may help to prevent Ulcerative Colitis and Ulcerative Colitis patients often experience Magnesium malabsorption. references

Vomiting may occur as a symptom of Magnesium deficiency. references

Ears and Hearing
Magnesium may help to prevent some types of Deafness: references
 Magnesium (especially the Magnesium Aspartate form) may help to prevent Noise-Induced Hearing Loss. references
Oversensitivity to Noise may occur as a result of Magnesium deficiency. references

Excretory System
Magnesium may strengthen the Bladder Muscles. [more info]
Magnesium may help to remove the substances that cause Body Odor from the body. [more info]
Magnesium Phosphate and Magnesium Sulfate (Epsom Salts) have been used as traditional remedies for alleviating Foot Odor. [more info]

Magnesium may reduce Inflammation of Kidney tissues. [more info]
Magnesium (400 - 600 mg per day) may inhibit Calcium Oxalate crystal formation in the Urine (Magnesium increases the solubility of Calcium Oxalate) and may thereby help to prevent Calcium Oxalate Kidney Stones: references

- Calcium Oxalate Kidney Stones are most likely to form in people who are deficient in Magnesium.
- The Urine of people who are prone to Calcium Oxalate Kidney Stones usually has a lowered Magnesium:Calcium ratio.
- Magnesium supplementation may be effective for preventing the reappearance of Calcium Oxalate Kidney Stones in persons who have previously had Kidney Stones.

Magnesium may alleviate Urinary Incontinence by strengthening the Bladder muscles within three months of initial supplementation. references

Eyes/Vision

Cataracts may occur as a result of Magnesium deficiency. references
Magnesium may alleviate or prevent Dry Eyes (due to its role in the production of Prostaglandin E7, a compound that is necessary for tear production). [more info]
Magnesium (243 mg per day for at least one month) may improve the visual field and peripheral Blood Circulation of Glaucoma patients: references

- Magnesium may help to prevent Glaucoma (by counteracting the toxicity of Glutamic Acid, a suspected cause of Glaucoma).

Magnesium may be essential for the development and maintenance of the Optic Nerve. references
Magnesium may be essential for the optimal function of the Retina. references

Immune System
Many (59% of) Acquired Immune Deficiency Syndrome (AIDS) patients are found to be deficient in Magnesium and supplemental Magnesium may help to prevent the loss of Helper T-Cells in AIDS patients. references
Magnesium deficiency may increase the risk of developing some forms of Cancer and Magnesium deficiency may increase the mortality rate from Cancer: references

- Magnesium may help to prevent Colon Cancer. references
- Magnesium may help to prevent Liver Cancer. references
- Magnesium may help to prevent Mouth Cancer (oral Cancer). references
- Magnesium may help to prevent Ovarian Cancer. references

Fever may occur as a symptom of Magnesium deficiency. [more info]
Magnesium may reduce Inflammation. references
Chronic Magnesium deficiency may cause abnormalities in the development of the Lymph Nodes. [more info]

Magnesium deficiency may impair the ability of Macrophages to function as Phagocytes. references
Chronic Magnesium deficiency may cause abnormalities in the development of the Spleen. references
Systemic Lupus Erythematosus (SLE) patients often exhibit abnormally low Magnesium levels. references

Chronic Magnesium deficiency may cause abnormalities in the development of the Thymus. [more info]

Metabolism: Blood Sugar
Magnesium may help to prevent Diabetes Mellitus and may help to keep Diabetes Mellitus under control (most Diabetes Mellitus patients are found to be deficient in Magnesium). references

- Magnesium supplementation may reduce the requirement for exogenous Insulin in Diabetes Mellitus Type 1 patients. references
- Deficient levels of intracellular Magnesium may contribute to the impaired Insulin response that occurs in Diabetes Mellitus Type 2. references
- Diabetes Mellitus patients may have a greater risk of (diabetic) Retinopathy if they are deficient in Magnesium than Diabetes Mellitus patients who are not deficient in Magnesium. references

Hypoglycemia may occur as a result of Magnesium deficiency. references
Insulin Resistance may occur as a result of Magnesium deficiency. references

Metabolism: Energy
Magnesium may improve Athletic Performance (via ATP production). references
Magnesium may facilitate the conversion of endogenous Glucose (blood sugar) into Energy (due to its role in the production of Adenosine Triphosphate (ATP)). references
Magnesium (Magnesium Aspartate form combined with Potassium Aspartate) may increase the capacity for prolonged Exercise (by up to 50%): references

- Supplemental Magnesium may counteract the accelerated excretion of Magnesium that occurs in people who engage in Endurance Exercise. references
- Magnesium may prevent Exercise-induced increases in Aldosterone and Cortisol levels.

Magnesium (especially the Magnesium Aspartate form of Magnesium when combined with Potassium Aspartate) may alleviate Fatigue (due to its role in the manufacture of Adenosine Triphosphate (ATP)). Magnesium supplementation may reduce the next-day Fatigue associated with Insomnia. references

- Magnesium (especially the Magnesium Aspartate form of Magnesium - 1,000 mg per day) may alleviate Chronic Fatigue Syndrome (CFS). references

Lethargy may occur as a result of Magnesium deficiency. references
Magnesium may increase Stamina (Magnesium deficiency may result in lowered Stamina). references

Metabolism: Lipids
Magnesium (especially the Magnesium Aspartate form) may lower total serum Cholesterol levels and elevated total serum Cholesterol levels may occur as a symptom of Magnesium deficiency: references

- Magnesium may increase HDL Cholesterol levels. references
- Magnesium may lower serum LDL Cholesterol levels and may inhibit the oxidation of LDL Cholesterol. references

Magnesium may help to lower elevated serum Triglycerides levels (where elevated serum Triglycerides occur as a result of Cholesterol loading). references

Metabolism: Liver
Cirrhosis may occur as a result of Magnesium deficiency. Cirrhosis patients often have low Magnesium levels. references
Magnesium deficiency may increase the body's susceptibility to Hepatitis infection. [more info]
Magnesium deficiency may accelerate the Aging Process in the Liver and may impair Liver function. references

Metabolism: Thyroid & Parathyroid
Some cases of Hyperparathyroidism may be attributable to Magnesium deficiency and supplemental Magnesium may alleviate such cases. references
Hyperthyroidism may occur as a result of Magnesium deficiency. [more info]

Metabolism: Weight
Magnesium may facilitate weight loss in persons afflicted with Obesity (due to its role in the production of Adenosine Triphosphate (ATP)). references

Musculoskeletal System: Bones
Magnesium is involved in the health of Bones (64% of the body's Magnesium is concentrated in the Bones). references
Magnesium may help to prevent Fractures (due to its ability to increase Bone Mineral Density). references
Magnesium deficiency may result in increased Osteoclast activity. references

Osteoporosis may occur as a result of Magnesium deficiency - women afflicted with Osteoporosis have been shown to have significantly lower Bone Magnesium than healthy women: references

- Magnesium may inhibit the ability of excessive Phosphorus to cause Osteoporosis.

Paget's Disease may cause low serum Magnesium levels (due to higher uptake of Magnesium into Bone). Therefore, Magnesium supplementation may be warranted for Paget’s Disease patients in order to avoid Magnesium deficiency. references

Musculoskeletal System: Muscles
Magnesium may help to reverse Cachexia (by enhancing the synthesis of endogenous Proteins and by restoring optimal production of Insulin-like Growth Factor-1 (IGF-1)). references
Magnesium may prevent Convulsions and Convulsions may occur as a result of Magnesium deficiency. references

Magnesium deficiency within Muscle cells is speculated to be a factor in the development of Fibromyalgia: references

- Daily supplementation of 300 - 600 mg of Magnesium (especially from the Magnesium Malate form) may result in significant improvements in the number of tender points in Fibromyalgia patients.
- Some researchers speculate that this improvement results from the Malic Acid content of Magnesium Malate rather than the Magnesium content, although there is also evidence that Magnesium may contribute significantly to the effectiveness of Magnesium Malate.

Magnesium may alleviate Muscle Cramps and Muscle Cramps may occur as a result of Magnesium deficiency: references

- Magnesium may alleviate the Muscle Cramps (leg Cramps) that often occur during Pregnancy.

Supplemental Magnesium (560 mg per day) may increase Muscle Strength. references
Muscle Tension may occur as a result of Magnesium deficiency and supplemental Magnesium may alleviate Muscle Tension: references

- Magnesium is responsible for the effectiveness of Epsom Salts (added to bath water) for alleviating Muscle Tension.

Muscle Weakness may occur as a result of Magnesium deficiency. references
Magnesium concentrates in the Muscles (26% of the body’s total Magnesium is stored in Muscles) - the role of Magnesium in the Muscles is to ensure that sufficient Oxygen is delivered to the Muscles. Magnesium is also required for Muscle movement and for the transmission of Nerve Impulses to the Muscles. references

Magnesium may alleviate Muscular Tics (by improving the electric conductance of Nerve Impulses at the junctions between the Nerves and Muscles) and Magnesium deficiency may be the underlying cause of Muscular Tics: references

- Blepharospasm (Tics of the Eyelids) may occur as a result of Magnesium deficiency (and supplemental Magnesium may alleviate Blepharospasm where Magnesium deficiency is the cause of Blepharospasm). references

Nervous System
[View Magnesium's Nervous System Health Benefits]


Oral Health

Magnesium may alleviate Bruxism. references
Magnesium may alleviate Periodontal Disease (by increasing the density of Alveolar Bone). references
Magnesium may harden Teeth and may prevent Tooth Decay (by stimulating the formation of Tooth Enamel): [more info]

- 1% of the body's Magnesium is concentrated in the Teeth.

Respiratory System

Asthma may occur as a result of Magnesium deficiency: references

- Magnesium may reduce the bronchoconstriction associated with Asthma by relaxing the (Smooth) Muscle around the bronchial tubes.
- Intravenous solutions containing Magnesium may successfully break acute Asthma attacks.

Chronic Obstructory Pulmonary Disease (COPD) patients are often found to have low (muscle but not serum) levels of Magnesium. Magnesium may help to prevent exacerbations of COPD. references
Globus Sensation (a sensation of Throat constriction) may occur as a result of Magnesium deficiency. references

Magnesium may improve the function of the Lungs: references

- In one study, subjects who consumed at least 380 mg of Magnesium per day exhibited superior Lung function compared to those consuming less than 380 mg of Magnesium per day regardless of whether the subjects smoked or not.

Sexual System

Magnesium (400 - 1,000 mg per day) may alleviate Dysmenorrhea (especially when Magnesium is administered together with Vitamin B6). references
Magnesium may alleviate Mastalgia (breast Pain) where Mastalgia is associated with Pre-Menstrual Syndrome (PMS). references

Magnesium may alleviate hot flashes (hot flushes) during Female Menopause. references
Menstruation may cause the depletion of Magnesium. [more info]
Women who experience Morning Sickness are often found to have abnormally low Magnesium levels, indicating that Magnesium deficiency may contribute to Morning Sickness. references

Magnesium may alleviate the Irritability, Fatigue, Depression and Edema associated with Pre-Menstrual Syndrome (PMS) - especially the PMS-C (Cravings) form of PMS. references
Magnesium may alleviate the Muscle Cramps (leg Cramps) that often occur during Pregnancy and may prevent/treat Preeclampsia. references

Magnesium deficiency may cause Premature Ejaculation. references
Prostate disorders may occur as a symptom of Magnesium deficiency. [more info]
Magnesium deficiency may be an underlying cause of (chronic) Prostatitis. references

Water & Water Balance

Edema may occur as a result of Magnesium deficiency. references

In-Tele-Health © 2009 (from Hyperhealth Pro CD-ROM)



http://www.arthritistrust.org/Articles/Magnesium%20Chloride%20Hexahydrate%20Therapy.pdf

 

Using magnesium chloride transdermally results in the rapid cellular-uptake of magnesium through the skin. By bypassing the digestive system all together, one does not need to focus on the many digestive problems that may hinder the bioavailability of magnesium.

The Institute produces Magnesium Chloride plus Zinc Sulphate ( a world first) in a known dosage (another world first) so that the all important calcium balance of  2:1 may be maintained.  A 200ml bottle plus 25ml spray bottle costs just $30.00 including P&P.

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