Coenzyme Q10 is an essential component of the mitochondrial electron transport process of respiration and coupled oxidative phosphorylation. It is therefore of fundamental importance to the intracellular energy producing systems. It has many useful applications in cellular energenics, including enhanced physical performance, oxygen utilization and endurance with reduced fatigue during and after exercise. Other areas of proven effectiveness include the cardiovascular system, the immune system and wound healing. Clinical Applications Cardiovascular disease Technical information Coenzyme Q10, also known as Ubiquinone, is a naturally occurring molecule, similar in structure to vitamin E. It is a co-factor in the electron transport chain, the biochemical pathway in cellular respiration from which ATP (adenosine tri-phosphate) and metabolic energy are derived. Since most cellular functions are dependent on availability of energy, Co Q10 is essential for the health of all human tissues and organs. Deficiencies of this substance have been reported in a wide range of conditions including cardiovascular disease, hypertension and periodontal disease. Animal studies have shown that the decline in Co Q10 levels that occurs with age may be partly responsible for age related deterioration of the immune system. The studies examining Co Q10 as a therapeutic agent indicate that it may protect tissues from damage that results from reduced blood flow. Co Q10 is an effective lipid soluble antioxidant and free radical scavenger. In performing this function, Co Q10 is capable of stabilizing cell membranes, calcium influx through membrane calcium channels and preventing depletion of metabolites necessary for the synthesis of ATP. Oral Co Q10 seems to have a low clearance rate from t |