Conjugated Linoleic Acid

"What goes around comes around". This saying certainly seems pertinent to the cholesterolmania promoted by the National Heart Foundation ably abetted by the National Health & Medical Research Council (NH&MRC) Australia for most of the past 30 years or more.

That is, that dietary cholesterol causes coronary artery disease and death! Therefore we should not eat too much beef, milk or cheese and most importantly substitute margarine for butter. This is at least the second largest fraud ever perpetrated on western society. You will never receive a "sorry, we were wrong", of that you may be sure.

The facts are that high cholesterol may contribute to cardiovascular disease but not often from a dietary source, and that margarine causes heart disease, cancer and asthma at least, and that butter, milk, cheese and beef are proven to treat and prevent obesity, heart disease and cancer, especially breast cancer. Therefore the NH&MRC and The National Heart Foundation must stand indicted for contributing to the uncontrolled escalation of Killer diseases and Chronic Illness conditions in our society since the promotion of margarine as part of a well balanced diet.

Conventional linoleic acid, the major component of corn oil, although having many specific health benefits is so far the only fatty acid proven to enhance cancer in experimental animals. So it is ironic that in its conjugated form, which is found mainly in animal fats and foods of animal origin, it is the most powerful naturally occurring fatty acid with proven ability to protect against cancer! In fact,  is the only known antioxidant/anticarcinogen primarily associated with animal foods. Moreover, amounts close to those in a normal mixed human diet are effective, not only in cancer protection but also in all the other biological activities of this compound.

Conjugated Linoleic Acid is a modified form of Linoleic Acid that contains double bonds [conjugation] along the 9th and 11th carbons in the Linoleic Acid molecule - there are actually 8 known isomers (different places on the Linoleic Acid molecule where double bonds may occur), but the type known as cis-9, trans-11 conjugated Linoleic Acid is the most biologically effective. Unlike "true" Linoleic Acid, Conjugated Linoleic Acid does not undergo the metabolic transformations associated with Linoleic Acid that lead to the production of Arachidonic Acid.

Health Benefits of Conjugated Linoleic Acid include but are not confined to: prevention of Atherosclerosis. Just 500mg of CLA per day  for 6 weeks fed to laboratory rabbits reduced atherosclerosis. CLA Potently inhibits the development of some cancers including breast cancer, colon cancer, and melanoma. CLA is a potent antioxidant being at least 200% more potent than beta-carotene. ClA facilitates weight loss in obesity at the same time facilitating muscle growth. Dietary sources for CLA are: Beef Tallow, Cheese, Milk, Beef, Veal, Chicken and Turkey   

Metagenics Keto Oil contains 2.4 grams per 5ml. The therapeutic dosage for cancer control is 3g per day.

References:
 Cook, M. E., et al. Conjugated linoleic acid (CLA) reduces backfat thickness, increases percent lean and improves feed efficiency in pigs. Presented at poster session at the Food Research Institute annual meeting. University of Wisconsin, Madison, USA. May 13, 1997.
 Pariza, M., et al. Conjugated linoleic acid (CLA) reduces body fat. FASEB Journal, 10:A560 (abstract 3227), 1996.
 Pariza, M., et al. Mechanism of body fat reduction by conjugated linoleic acid. Federation of American Societies for Experimental Biology Journal. 11(3):A139, 1997.
West, D. B., et al. Reduced body fat with conjugated linoleic acid feeding in the mouse. Federation of American Societies for Experimental Biology Journal. 11(3):A599, 199
Decker, E. A. The role of phenolics, conjugated linoleic acid, carnosine, and pyrroloquinoline quinone as nonessential dietary antioxidants. Nutr Rev. 53:49-58, 1995.
Shultz, T. D., et al. Inhibitory effect of conjugated dienoic derivative of linoleic acid and beta carotene on the in vitro growth of human cancer cells. Cancer Letters. 63:125-133, 1992.
· Pariza, M. W., et al. Formation and action of anticarcinogenic fatty acids. Adv Exp Med Biol. 289:269-272, 1991.
Shultz, T. D., et al. Inhibitory effect of conjugated dienoic derivative of linoleic acid and beta carotene on the in vitro growth of human cancer cells. Cancer Letters. 63:125-133, 1992.
Ip, C., et al. Conjugated linoleic acid: A powerful anticarcinogen from animal fat sources. Cancer. 74(3):1050-1054, 1994.
Ip, C., et al. Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat. Cancer Research. 54(5):1212-1215, 1994.
Shastri, S. CLA. Conjugated Linoleic Acid - vital spark for a lean body. Total Health. 19(4):44-45, 1997.
Shastri, S. CLA. Conjugated Linoleic Acid - vital spark for a lean body. Totalhealth. 19(4):44-45, 1997.
Cornell, K. K., et al. Conjugated linoleic acid inhibited the in vitro proliferation of canine prostate cancer cells. Federation of American Societies for Experimental Biology Journal. 11(3):A579, 1997.
Shastri, S. CLA. Conjugated Linoleic Acid - vital spark for a lean body. Totalhealth. 19(4):44-45, 1997.
 Lee, K. N., et al. Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis. 1(108):19-25, 1994.
Ferreira, M., et al. Effects of CLA supplementation during resistance training on body composition and strength. NSCA Conference and Exhibition Program. Page 168, 1997.
Hayek, M. G., et al. The effect of conjugated linoleic acid (CLA) on the immune response of young and old mice. Federation of American Societies for Experimental Biology Journal. 11(3):A580, 1997.
Shastri, S. CLA. Conjugated Linoleic Acid - vital spark for a lean body. Totalhealth. 19(4):44-45, 1997.
Chinn, S., et al. Conjugated linoleic acid is a growth factor for rats as shown by enhanced weight gain and improved feed efficiency. Journal of Nutrition. 124:2344-2349, 1994.
Cook, M. E., et al. Immune modulation by altered nutrient metabolism: Nutrional control of immune-induced growth depression. Poultry Science. 72(7):1301-1305, 1993.
Kreider, R., et al. Effects of conjugated linoleic acid (CLA) supplementation during resistance training on body composition and strength. J Strength Cond Res. 1997.
Miller, C. C., et al. Feeding conjugated linoleic acid to animals partially overcomes catabolic responses due to endotoxin injection. Biochemical and Biophysical Research Communications. 198(3):1107-1112, 1994.
Ferreira, M., et al. Effects of CLA supplementation during resistance training on body composition and strength. NSCA Conference and Exhibition Program. Page 168, 1997.
Shastri, S. CLA. Conjugated Linoleic Acid - vital spark for a lean body. Totalhealth. 19(4):44-45, 1997.
Shastri, S. CLA. Conjugated Linoleic Acid - vital spark for a lean body. Totalhealth. 19(4):44-45, 1997.
Hayek, M. G., et al. The effect of conjugated linoleic acid (CLA) on the immune response of young and old mice. Federation of American Societies for Experimental Biology Journal. 11(3):A580, 1997.

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