Geoffrey Leigh
MSc.,ND.D.N.Sc.

ProResolvin TO THE RESCUE.
A clinical study was conducted by Dr. Andrew Flowers at Southern Cross University (Australia) in 2001 to assess the anti-inflammatory action and potency of ProResolvin, a Glycosaminoglycan Complex (APO1000946) compared to Aspirin (Aspirin 50µM), Glucosamine, Chondroitin Sulphate powder (APO 1000943), Chondroitin sulphate tablets (APO 1000944), and Bovine Tracheal Cartilage (liquid), (APO 1000945).

The solvent control was 5µL H₂0. (23187)

The final result demonstrated that ProResolvin was up to a massive 32 times the anti-inflammatory action of the other substances tested. Hereunder is the Table of comparisons.

Understanding that these statistics may mean little or nothing to the non-mathematical, what is interesting if not a revelation, is the fact that Aspirin obviously inhibits the conversion of PGE₂ thus exhibiting its anti-inflammatory action.

In contrast the Chondroitin's and Cartilage which contains Chondroitin exert a different action and therefore must act through a pathway other than the synthesis of PGE₂ from PGH_{2 .} Dr Flowers stated: "These results show that these products (Chondroitin’s & Cartilage), although successful (in clinical trials) in the treatment of inflammatory processes, must act through a pathway other than the synthesis of PGE₂ from PGH₂."

ProResolvin is extracted from the tracheal cartilage of bovine calf less than 18 months days old.,Then through its unique production method as never before, the *Glycosaminaglycans are extracted in their entirety.

*Glycosaminoglycans are a group of polysaccharides that are usually comprised of two repeating sugar units, one of which is a hexosamine (an amino sugar - often glucosamine or galactosamine) bound to sulphur.

Most people are not aware of the very effective anti-inflammatory role of glycosaminoglycans, which include but are not confined to:
Cardiovascular System:
Glycosaminoglycans maintain the elasticity of blood vessels.
Glycosaminoglycans also lower LDL cholesterol and raise HDL cholesterol,
and therefore effectively treat and prevent Heart disease.
Musculoskeletal System:
Glycosaminoglycans are a major constituent of the proteoglycans content of cartilage, and are present in the extra cellular matrix in most regions of the body. Depletion of glycosaminoglycans from cartilage is in fact the primary underlying mechanism during the progression of osteoarthritis.
Skin:
Glycosaminoglycans help to retain water in the skin and thereby help to prevent dry skin, and associated problems.
It is the endogenous glycosaminoglycans that are involved in the wound healing process, including post-operative wound healing where they contribute to the formation of the matrix of scar tissue.

Glycosaminoglycans enhance the function of proteoglycans, which are composed of glycosaminoglycans bound to proteins. Chondroitin Sulfate comprises approximately 92% of the proteoglycans content of normal cartilage, and Keratan Sulfate comprises approximately 8% of the proteoglycans content of normal cartilage. All of the abovementioned beneficial substances are found in ProResolvin

Therefore ProResolvin may be indicated in all of the following:

As modern research methods increase in sophistication, Inflammation has been tentatively linked as an underlying cause of various ailments that were previously believed to be unrelated to Inflammation including:

Aging Process
Alzheimer’s Disease
Atherosclerosis
Cancer
Congestive Heart Failure
Osteoporosis
Periodontal Disease
Stroke
Thrombosis

SUMMARY
ProResolvin does not reduce inflammation along the same pathway as the Non-Steroidal-Anti-inflammatories (NSAIDs), which in the long term destroy joint function.

ProResolvin is specially formulated and produced by a unique extraction method from totally natural substances and therefore is free of untoward side effects.

 •        The recommended dosage of ProResolvin®  is 10ml once daily from a spoon, in water, milk, juice or food, however, this can be safely increased to twice daily initially for maximum effect

•        Many patients have reported a reduction in discomfort as soon as 7 days after beginning ProResolvin® but results will  obviously vary between individuals.

The price per 200ml bottle is $45.00 including pack & post

We welcome distributors and especially worldwide.

We are proud to be a major distributor. Proceeds to medical research and health promotion.

Copyright © (2006) Australian Institute of Biological Medicine