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Andro NK
Natural Killer (NK) Cell Regulation
A powerful combination of nutrients and high potency herbal extracts
that have been specifically tailored to boost immunity, and regulate cytokine levels and
NK cell function, thereby reducing the severity and duration of the symptoms of viral
infections. Important in Cancer protocols where chemotherapy is not applied.
Herbs and Nutrients that may Assist
Cats Claw (Uncaria tomentosa)
King of Bitters/Chiretta (Andrographis paniculata)
Wild Yam (Dioscorea villosa)
Zinc
Manganese
Vitamin E
Dosage: 2-6 tablets daily
Clinical Applications
Chronic infections:
Recurrent colds and flu
Epstein-Barr Virus
Barmah Forest Virus
Ross River Virus
Cytomegalovirus
Herpes Virus
Human Immunodeficiency Virus
Etc.
Chronic Fatigue Syndrome
Any condition of reduced immune competence
Scientific Research
- Andrographis paniculata
, while widely used in traditional Ayurvedic medicine for
infections and infestations, actually shows no antibacterial activity, - the
evidence points instead to immune enhancing activity. It increases phagocytosis1,
and both the antibody-specific and the non-specific immune responses. It has a
demonstrable effect in reducing the symptoms of the common cold. It is also of equal or
greater potency to St. Marys Thistle as a hepatoprotective and choleretic,,.
Prior administration of Andrographis has prolonged survival after snakebite, and it has
proven effective against nematodes such as Ascaris spp,. No toxicity has been
recorded but it can reduce fertility,, and is thus contraindicated in
pregnancy.
- There are at least 13 related species of plant known as Cats Claw (Uņa de Gato in
Spanish), but the major interest is in Uncaria tomentosa, a woody vine that grows
to over 350 metres in length. The inner bark is traditionally used to treat an
extraordinarily broad range of conditions: e.g. arthritis, gastritis, asthma, gastric
ulcer, diabetes, cancers, viral infections, menstrual disorders, convalescence and
debility. This capacity to treat such diverse conditions is in part explained by the
discovery of immune-stimulating oxindole alkaloid constituents, the most active being
isopteropodine. These have been found to stimulate phagocytosis14. Extracts of
Cats Claw have demonstrated anti-inflammatory, antimutagenic, anticancer13
and antitumour13 activity. It has also been effective in the treatment of viral
conditions, including herpes and HIV.
- Wild Yam (Dioscorea villosa) is well known for its steroidal anti-inflammatory
activity. Its inclusion stems from its lesser-known capacity to increase DHEA levels when
these are depressed; for instance in chronic conditions like Chronic Fatigue Syndrome. It
has no effect on persons with normal DHEA levels. DHEA is the hormonal precursor to
testosterone and oestrogen derived from pregnenolone. Increased demand for cortisol (owing
to stress, toxicity or infection) depletes pregnenolone, and hence DHEA. Dioscorea may
exert a cortisol-sparing action via its anti-inflammatory action that in turn frees more
pregnenolone for conversion to DHEA and the gonadal hormones.
- Vitamin E and Manganese
have both been shown to reduce excess inflammatory cytokine
levels, thereby reducing the oxidative damage to lymphocytes (NK cells) and improving the
clearance of infective agents.
- Zinc
in a specialised chelated form designed to enhance absorption has been shown to
exert supportive actions on multiple pathways involved in the regulation of lymphocyte
function.
References
1 Chang H M and But P P. Pharmacology and Applications of Chinese Materia Medica, Vol
2. World Scientific 1987.
2 Leelarasamee A et al. J Med Assoc Thailand. 1990; 73,299.
3 Puri A et al. J Natural Products. 1993; 56,995.
4 Melchior J, Palm S, Wikman G. Controlled clincial study of standardized
Andrographis paniculata extract in common cold - a pilot trial. Phytomedicine. 1996/97; 3
(4): 315-318.
5 Tripathi G S and Tripathi Y B. Phytotherapy Res. 1991; 5,176.
6 Shukla B et al. Plant Medica. 1992; 58,146.
7 Visen P K et al. J Ethnopharmacology. 1993; 40,131.
8 Martz W. Toxicon. 1992; 30,1131.
9 Dutta A and Sukul N C. J Helminthology. 1982; 56,81.
10 Raj R K. Ind J Physiol Pharmacol. 1975; 19.
11 Akbarsha M A et al. Ind J Exp Biol. 1990; 28,421.
12 Zoha M S et al. Banglasdesh Med Res Council Bull. 1989; 15,34.
13 Blumenthal M. Una de Gato (Cat's Claw): Rainforest herb gets scientific and
industry attention. Whole Foods (Herb Clip). 1995; 62-5.
14 Wagner H, Kreutzkamp B, Jurcic K. The alkaloids of Uncaria tomentosa and their
phagocytosis-stimulating action. Planta Medica. 1985; (5): 419-23.
15 Senatore A et al. Phytochemical and biological study of Uncaria tomentosa.
Bollettino - Societa Italiana Biologia Sperimentale. 1989; 65(6): 517-20.
16 Rizzi R et al. Mutagenic and antimutagenic activities of Uncaria tomentosa and
its extracts. Journal of Ethnopharmacology. 1993; 38 (1): 63-77.
17 Steinberg P. Cat's Claw (una De Gato). The Herb Quarterly. 1994.
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